Pulmonary fibrosis in an individual occupationally exposed to inhaled indium-tin oxide.

نویسندگان

  • S Homma
  • A Miyamoto
  • S Sakamoto
  • K Kishi
  • N Motoi
  • K Yoshimura
چکیده

Despite the increasing industrial use of indium-tin oxide (ITO) to manufacture flat-panel displays, such as liquid-crystal displays or plasma display panels for televisions, little is known about the potential health hazard induced by occupational exposure to indium compounds. The current study describes a case of fibrotic lung disease that developed after a 4-yr exposure to ITO. The pathology of the lung demonstrated pulmonary fibrosis with the presence of cholesterol granulomas. In conclusion, more attention needs to be paid to the possible toxic effects of indium compounds, and maximum healthcare measures should be taken to protect industry workers from these toxicities.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Two- and 13-week inhalation toxicities of indium-tin oxide and indium oxide in rats.

OBJECTIVES Two- and 13-week inhalation toxicities of indium-tin oxide (ITO) and indium oxide (IO) were characterized for risk assessments of workers exposed to ITO. METHODS F344 rats of both sexes were exposed by inhalation to ITO or IO aerosol for 6 h/day, 5 day/wk for 2 wk at 0, 0.1, 1, 10 or 100 mg/m(3) or 13 wk at 0, 0.1 or 1 mg/m(3). An aerosol generator and inhalation exposure system wa...

متن کامل

Inhalation carcinogenicity and chronic toxicity of indium-tin oxide in rats and mice.

OBJECTIVES Carcinogenicity and chronic toxicity of indium-tin oxide (ITO) were examined by inhalation exposure of rats and mice to ITO aerosol. METHODS Fifty mice of both sexes were exposed to ITO at 0 (control), 0.01, 0.03 or 0.1 mg/m(3) for 6 h/day, 5 day/wk for 104 wk, and 50 rats of both sexes were exposed to 0, 0.01 or 0.03 mg/m(3) ITO for the same time period. The repeated exposure of 5...

متن کامل

Pulmonary toxicity in mice by 2- and 13-week inhalation exposures to indium-tin oxide and indium oxide aerosols.

OBJECTIVES Inhalation toxicities of indium-tin oxide (ITO) and indium oxide (IO) in mice were characterized in comparison with those previously reported in rats. METHODS B6C3F(1) mice of both sexes were exposed by inhalation to ITO or IO aerosol for 6 h/day, 5 day/wk for 2 wk at 0, 0.1, 1, 10 or 100 mg/m(3) or 13 wk at 0, 0.1or 1 mg/m(3). RESULTS ITO and IO particles were deposited in the l...

متن کامل

Synthesis and Morphology Study of Nano-Indium Tin Oxide (ITO) Grains

In this paper, indium tin oxide (ITO) nanoparticles has been prepared by chemical methods under given conditions with solution of indium chloride (InCl3·4H2O), tin chloride (SnCl4·5H2O) in ammonia solution. The samples were characterized by X-ray Diffraction (XRD) and scanning electron microscopy (SEM) analyses after heat treatments. The SEM results showed that, the size of the ITO particles pr...

متن کامل

Synthesis and Morphology Study of Nano-Indium Tin Oxide (ITO) Grains

In this paper, indium tin oxide (ITO) nanoparticles has been prepared by chemical methods under given conditions with solution of indium chloride (InCl3·4H2O), tin chloride (SnCl4·5H2O) in ammonia solution. The samples were characterized by X-ray Diffraction (XRD) and scanning electron microscopy (SEM) analyses after heat treatments. The SEM results showed that, the size of the ITO particles pr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The European respiratory journal

دوره 25 1  شماره 

صفحات  -

تاریخ انتشار 2005